Transmissible veneer tumor: retrospective study of 102 cases (2006-2017)

Abstract

The objective of this study was to describe a retrospective study of 102 cases of transmissible venereal tumor from the year 2006 to 2017. A total of 102 cases of Transmissible Venereal Tumor (TVT) were studied and sent to the Animal Pathology Laboratory of the Centro Universitário Integrado, Campo Mourão - PR, during the period from 2006 to 2017. The criterion for inclusion of this study was to confirm the diagnosis of TVT by cytologies, stained by Giensa method 5%. Of the 102 cases studied, we analyzed sex, higher tumor prevalence in females with 53 cases, and 49 in males. The localization of the tumor lesion, 81 in the genital region with the highest prevalence, 13 cases in the skin, 12 in the oral / nasal region and 1 case in the ocular region. The characteristics of lesion were analyzed: of the 102 cases, 77 were ulcerated. In 90 cases the lesions were focal and multifocal in 11 cases. In general microscopy it was possible to observe that the samples are quite cellular, the cells are round with abundant basophilic and vacuolated cytoplasm, the nucleus is round, coarse and single and prominent nucleolus, figures of mitoses are frequent, and inflammatory cells are observed. Most of the cases had cellular atypia and binucleate cells. It was concluded that the most affected dogs were female, and that the location of the lesions has a greater predominance of the focal type lesion and in the genital region. Serosanguinolent secretion and ulcerations were frequent, the cytological examination is fundamental to confirm neoplasia diagnosis.